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Process design2$B7o(B
Near-Infrared Spectroscopy2$B7o(B
Sterile drug product manufacturing2$B7o(B
Process integration1$B7o(B

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13$BE,1~7?%=%U%H%;%s%5!<$*$h$S?dDjCM$NJ?3j2=$r
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soft sensor
offline analysis
online analysis
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15Process performance assessment based on stochastic simulation in sterile drug product manufacturing
(U. Tokyo) ($B3X(B)$B!{(BCasola Gioele$B!&(B (Hoffmann-La Roche) Siegmund Christian$B!&(B Mattern Markus$B!&(B (U. Tokyo) ($B@5(B)Sugiyama Hirokazu
Performance Assessment
Sterile Drug Product Manufacturing
Stochastic Simulation
O
26$B%R!<%H%P%i%s%92r@O$N8zN(2=$H%W%i%s%H@-G=Nt2=4F;k$N0Y$N?7$7$$;XI8$H
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enthalpy
heat balance
performance monitoring
O
71[$BM%=(O@J8>^(B] $BFbItG.8r497?>xN1Ec$N:GE,9=B$9g@.(B
($B5~Bg1!9)(B) ($B3X(B)$B!{9b@%(B $BMN;V(B$B!&(B ($B@5(B)$BD9C+It(B $B?-<#(B
Process Synthesis
Energy Saving
Linear Formulation
O
80$B0eLtIJO"B3@=B$$rBP>]$H$9$k%W%m%;%9%7%9%F%`9)3X8&5f(B
($BElBg1!9)(B) ($B@5(B)$B!{?y;3(B $B90OB(B$B!&(B ($B3X(B)$B>>JB(B $B8&:n(B
Pharmaceutical manufacturing
Continuous manufacturing
Process design
O
174$B0eLtIJ@=B$$K$*$1$k2a;@2=?eAG$rMQ$$$?=|@w%W%m%;%9$N%b%G%k9=C[(B
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Process design
Sterile drug product manufacturing
Isolator
O
241CZ$BK!$rMxMQ$7$?(B300 mm$B%7%j%3%sC17k>=@=B$%W%m%;%9$N%0%l%$%\%C%/%9%b%G%j%s%0(B
($B5~Bg9)(B) ($B@5(B)$B@%8M(B $B$B!&(B ($B@5(B)$B!{6b(B $B>090(B$B!&(B ($B5~Bg>pJs(B) ($B@5(B)$B2CG<(B $B3X(B$B!&(B (SUMCO) ($B@5(B)$BF#86(B $B=S9,(B$B!&(B ($B@5(B)$B?eED(B $B6)I'(B$B!&(B ($B5~Bg9)(B) ($B@5(B)$BD9C+It(B $B?-<#(B
Czochralski process
Single-crystal silicon
Gray-box model
O
346$BN`;wEY$K4p$E$/%7%j%3%s%&%'!<%O$NJ?C3EYD4@0(B
(SUMCO) ($B@5(B)$B!{?eED(B $B6)I'(B$B!&(B ($B5~Bg>pJs(B) ($B@5(B)$B2CG<(B $B3X(B
silicon wafer
flatness
similarity
O
417$B0[>o7QB3;~4V$K4p$E$/;~7ONs%/%i%9%?%j%s%0$K$h$k0[>o>uBVA+0\$N2D;k2=(B
(NEC) ($B@5(B)$B\'ED(B $B>;>0(B
Clustering
Fault localization
Invariant networks
O
503$BN.F0AX4%Ag%W%m%;%9$K$*$1$k?eJ,NL$N%j%"%k%?%$%`%b%K%?%j%s%0(B
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Fluidized Bed Drying
Near-Infrared Spectroscopy
Moisture
O
508$B5<;w0\F0AX<0%/%m%^%H%0%i%U%#!
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Near-Infrared Spectroscopy
Simulated Moving-Bed
Chromatography
O
592$BJQ?t=|5n4sM?$K$h$k0[>oMW0xF1Dj(B:$B?];@%S%K%k@=B$%W%i%s%H$X$NE,MQ(B
($B5~Bg>pJs(B) ($B3X(B)$B!{N$;3(B $BM:N<(B$B!&(B ($B@5(B)$BF#86(B $B9,0l(B$B!&(B ($B@5(B)$B2CG<(B $B3X(B
fault identification
multivariate statistical process control
kernel principal component analysis
O
594$B?];@%S%K%k@=B$%W%i%s%H$X$N(B2$B<+M3EY(BE-FRIT$B$NE,MQ(B
($B5~Bg>pJs(B) ($B3X(B)$B!{D%(B $B?DBz(B$B!&(B ($B@5(B)$B2CG<(B $B3X(B$B!&(B ($B%"%:%S%k(B) ($B@5(B)$B>.2O(B $B$B!&(B ($B
two-degree-of-freedom PID control system
extended fictitious reference iterative tuning
data-driven controller tuning
O
608$B%"%/%F%#%S%F%#$,A4BNG<4|$r2!$7$F$$$kEY9g$$$r7W;;$G5a$a$kJ}K!$K$D$$$F(B
($B5\:jBg(B) ($B@5(B)$B!{9bDM(B $B2BBe;R(B$B!&(B ($B@5(B)$B;3>l(B $B5W><(B$B!&(B $B5WJ]ED(B $B??0lO:(B$B!&(B $B2,:j(B $BD>@k(B
Scheduling management
DRAG
Float
O
617$BH?1~$HJ,N%$r4^$`@=B$%W%m%;%9$K$*$1$k%^%k%A%W%m%@%/%H$H%^%k%A%?%9%/$NHf3SI>2A(B
($BFAEgBg1!M}9)(B) ($B3$(B)$B!{%"%k%+%s%?%i(B $B%"%S%i(B $B%X%9!<%9(B $B%i%U%!%(%k!&(B ($B@5(B)$B30NX(B $B7r0lO:(B$B!&(B ($B@5(B)$BKY2O(B $B=S1Q(B
Process modeling
multi-task manufacturing
reaction-separation systems
O
807$BJBNs%^%$%/%m%j%"%/%?$NJD:I?GCG$N$?$a$NN.BNJ,G[!&<}=8AuCV@_7W$H%;%s%5G[CV(B
($B5~Bg1!9)(B) ($B3X(B)$B!{DT(B $BNJB@O:(B$B!&(B ($B3X(B)$BB?2l(B $BIRZv(B$B!&(B ($B@5(B)$BEBB<(B $B=$(B$B!&(B ($B@5(B)$BC+8}(B $BCR(B$B!&(B ($B@5(B)$BD9C+It(B $B?-<#(B
Microreactor blockage diagnosis
Flow distributor design
Sensor location
O
812$BGQG.MxMQ7?%a%A%k%7%/%m%X%-%5%sC&?eAGH?1~%7%9%F%`(B
($B;:Am8&(B) ($B@5(B)$B!{G.3$(B $BNIJe(B$B!&(B ($B@5(B)$B>>K\(B $B=(9T(B$B!&(B $B>.Eg(B $B9(0l(B$B!&(B $BDTB<(B $BBs(B
Hydrogen energy
Methylcyclohexane
Process integration
O
817$BIT3N
($BL>Bg1!9)(B) ($B3X(B)$B!{:#2,(B $BPRB@(B$B!&(B ($B@5(B)$B66D^(B $B?J(B$B!&(B ($B@5(B)$BLpV:(B $BCRG7(B$B!&(B ($B0&9)Bg>p(B) ($B@5(B)$B>.LnLZ(B $B9nL@(B
improvement of process completion time
critical path
system with uncertainty
O

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(C) 2016 $B8x1W
Most recent update: 2016-11-29 11:54:01
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