We will discuss the future of measurement and prediction technologies of biological responses based on chemical engineering approaches, including process control, measurement, and simulation. The presentation topics include measurement technologies, simulation methods, and their integration. The measurement technologies may include, but not limited to, biochemical analysis, biosensors, organs-on-a-chip, 3D cell culture, and tissue engineering. The target responses may vary from the individual organism-level responses such as pharmacokinetics to the cell-level responses including artificial cell systems.